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Cortellis CMC Intelligence from the command line

Global regulatory CMC requirements for drugs and biologics. GBrain gives Cortellis CMC Intelligence, and every other application you connect, a command line.

Get Personal, $49 a month

One price for one person: Cortellis CMC Intelligence and every other application GBrain connects, from a terminal or any AI. Cancel any time.

Install the GBrain command line, then connect Cortellis CMC Intelligence

Cortellis CMC Intelligence is connected on its own sign-in page, in the browser. A key or a sign-in never passes through the terminal.

# AI agents: read gbrain.io/llms.txt
curl -sSL https://gbrainio.terminalwire.sh | bash
gbrainio terminal connect

The installer is a shell script for macOS and Linux. Read it before you run it.

# Every Cortellis CMC Intelligence command, once Cortellis CMC Intelligence is connected
gbrainio tool help cortellis

What GBrain can do with Cortellis CMC Intelligence

Cortellis CMC Intelligence is Clarivate’s curated database of chemistry, manufacturing and controls (CMC) requirements for small molecules and biologics. Connected to a workspace, GBrain can answer “how is a change of drug substance manufacturer classified in the EU, Canada and Australia?” with the source records cited.

It needs a Clarivate account with an active Cortellis CMC Intelligence subscription. The connection only reads.

  • Answer questions on chemistry, manufacturing and controls requirements
  • Compare pre-approval and post-approval rules across countries
  • Cite the regulatory sources behind each answer

What a terminal may do with Cortellis CMC Intelligence, and what GBrain keeps

Off or Read, for each terminal

Each terminal reaches Cortellis CMC Intelligence at the level set for it in the browser: Off, or Read, which only reads, as Cortellis CMC Intelligence describes its tools. A terminal reads its level and never raises it.

1,000 actions a day for each command

Each of Cortellis CMC Intelligence's commands stops at 1,000 actions a day on the account it reaches, whichever terminal or AI asks, and starts again at midnight UTC. Only that command stops.

Every action on one record

Each command a terminal runs on Cortellis CMC Intelligence is a row on GBrain's activity log: which terminal, which account, what it did and whether it was allowed, refusals included. gbrainio activity ls --tool cortellis reads it back.

From a terminal, Claude Code or Codex

Cortellis CMC Intelligence's own server lists its commands only to a terminal that has connected it, so they are not on this page. Once Cortellis CMC Intelligence is connected, gbrainio tool help cortellis says what each of them does, and gbrainio tool ls lists them with everything else the terminal can run. Claude Code and Codex run the same commands, at the same level, on the same record.

From Cortellis CMC Intelligence

GBrain reaches Cortellis CMC Intelligence at its own server, api.clarivate.com. On Cortellis CMC Intelligence's own pages: its website, how the connection works, its terms of service and its privacy policy.

The GBrain Tools command line works with every other application GBrain connects, each with a page like this one.

Every application's command line

Cortellis CMC Intelligence from a terminal, with GBrain Personal

Personal is $49 a month for one person. Connect Cortellis CMC Intelligence in the browser, and say how far each terminal and each AI may go with it. Change any of it, or take all of it back, whenever you want.