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Open Targets

Evidence linking drug targets to diseases.

Install It is public, so there is nothing to sign in to.

What GBrain can do with Open Targets

Open Targets is a public-private initiative that builds evidence on therapeutic drug targets from genome-scale experiments and public datasets. Its platform scores target-disease associations and annotates targets, diseases, drugs, variants and GWAS studies. Connected to a workspace, GBrain can answer “which targets have the strongest evidence for Crohn’s disease?”

No sign-in is needed, and the connection only reads.

  • Search targets, diseases, drugs and variants
  • Query target-disease associations and scores
  • Pull GWAS studies, credible sets and annotations

From the command line

GBrain gives Open Targets a command line too. From a terminal, a script or Claude Code, gbrainio tool help open-targets lists its commands once it is connected.

Open Targets from the command line

Install Open Targets in a workspace

It is public, so there is nothing to sign in to. Then add it to a workspace, and anyone on the team can ask about it in plain words.